Melanotan 2 Recent News
Melanotan 2 is an analog of the naturally occurring alpha-melanocyte-stimulating hormone (alpha-MSH). The alpha-MSH is an endogenous hormone that is produced in the pituitary gland. According to melanotan 2 reviews, the anterior lobe of the pituitary gland produces the peptide which is effective in inducing sunless tanning. Current research shows that the peptide accentuates libido in mice when they are injected with the peptide. The male mice solicit the female mice and they experience erections. The female mice, on the other hand, have reddened sexual organs and they experience lordosis. The mechanism of action of melanotan 2 is through biomimicry which is the production of the hormone endogenously. The melanocortin receptors are essential in bringing about the effects of the peptides. Lack of sensitivity to the hormone leads to overweight and poor growth as aboserved in mice under research.
Melanotan 2 and Hunger
Melanocortin receptors play a crucial role in the response to leptin, a peptide which signals satiety. Lack of leptin leads to ingestion of excess food and weight gain. Leptin is regulated by neurons referred to as proopiomelanocortin neurons. These neurons activate the mechanism from the central nervous system. When the organism lacks sensitivity to leptin, there is increased food intake and deposition of fats in the peripheral organs. Research indicates that melanotan 2 is an agonist and it works alongside the natural hormone to enhance leptin response. The activation of melanocortin receptor 4 has shown to have an impact on the amount of food ingested. Research on mice indicates that the rodents with deficiency in leptin tend to consume fatty meals compared to those without the deficiency. Consumption of fats will contribute to the deposition of fatty acids and glycerol in the peripheral and visceral organs. This is the main contributor to weight gain.
According to melanotan 2 reviews, when the synthetic peptide is administered, it has a positive feedback mechanism on the system and the alpha-melanocyte stimulating hormone production. Moreover, research shows that melanotan 2 contributes to weight loss. The mechanism of action is through accentuation of leptin sensitivity and the breakdown of food and nutrients supply to the fat cells or adipocytes. Melanotan 2 has molecules in the chain, which target specific fat cells. When the cells are stimulated, they induce the development of muscles and burning of excess fat in the muscles. There are various hormones that are known to contribute to fat burning and melanotan 2 is one of the most effective peptides. The change of arginine and glutamic acid in the chain has increased the sensitivity of melanotan 2 and its potency. Since the peptide promotes protein synthesis, cuts supply of nutrients and blood supply to the fat cells, it promotes weight loss. The increase in protein synthesis, decrease in cell generation and an increase in glucose transport are some of the most fundamental aspects of any living organism. The adipocytes degrade and they are removed naturally since the fat cells die in large numbers, then the weight loss is quite significant.