An endocrine hormone that is produced in the liver. It’s five times more powerful than IGF-LR3 and ten times more powerful than regular base IGF-1.

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Product Description

Buy IGF-1 DES Online- Muscle building and Tissue growth properties

IGF DES is a polypeptide which is secreted by the liver. The structure of the polypeptide is made up of 67 amino acids and it has a molecular weight 0.7371. The structure is highly reactive which means it has muscle building and tissue growth properties. The repair of various chemical complex molecules, Other names that the peptide is referred to are IGF 1, IGF1, insulin-like growth factor 1 and somatomedin C.

The primary impetus of IGF DES is in the ability to accentuate hyperplasia or muscle building which in some cases is also called hypergenesis. In essence, IGF DES  promotes the cell division, differentiation, development and maturity to enhance growth. This helps to increase the number of cells in different parts of the body. The peptide is initiated when there is a trigger to produce new cells and tissues, mostly if there is tissue overload or cell damage. In other cases, production of IGF DES is initiated when there is the need to gain a semblance of stabilization or when there is skin loss.

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Mechanism of Action

Mechanism of Action
Mechanism of Action

Hyperplasia can be initiated when there is hormonal dysfunction. This in turn causes the proliferation to alleviate that could develop when the performance of different tissues. In some instances, the process can be triggered by a response to inflammatory condition. This can make the body compensate for the inflammation which can cause cell loss. Since research has shown that IGF DES has the ability to initiate hyperplasia. There are continuing studies which are geared towards the targeted ability to regulate and control the growth of tissues at the cellular level. One of the major aspects is the ability to influence in neurological growth.IGF DES can be of use in containing the capacity control and regulate both neuronal structure and functionality. Moreover, studies are underway to determine the ability of IGF DES in maintaining nerve cell function which is essential in promoting neuroregeneration. This function has been in testing to ascertain if the peptide can be used in treating injuries affecting the central nervous system.

Studies revealed that the ability to promote hyperplasia could be because IGF DES  can initiate muscle formation through cell division. This can be manipulated to help deal with muscular injuries that can be alleviated with the peptide. Cell division process can be centered on areas where new cells are required. This could promote quick muscle healing and the ability to increase muscle growth.


One aspect of this feature is to slow down the aging process since myoblasts play a crucial role in aging. Increasing their count can help reduce the intensity at which the cells die off. The research revealed that IGF DES can promote the generation of new cells and slow down the degradation of muscle cells while regulating skin elasticity and flexibility. In sports, one of the main concerns is muscle injury. One of the expected uses of IGF DES is to help in muscle regeneration. This is important in improving recovery time as well as alleviating age-related conditions at a later stage. However, IGF DES  has not been approved for use in humans it is still under research.

IGF-1 DES Synthesis

IGF DES is a cleaved version of the insulin-like growth factor 1. The truncated version is commonly referred to as somatomedin C. Research showed that the cleaved peptide is 10 times more effective and more potent that the naturally produced hormone. The efficacy comes in the proliferation of cells and stimulation of the hypertrophy. Moreover, the synthetic version is more active because glutamate is removed from the amino acid in position 3. Naturally, synthesized insulin-like growth factor 1 can also be called somatomedin C, depending on the presentation or the context of the application. This is one essential protein that is encoded by the animal’s genomic sequence in the IGF gene. This is the sulfation factor that causes certain unique effects in the system of the organism. This is through the non-suppression of insulin-like activity. IGF DES  is naturally produced in the liver as indicated earlier. However, there are other alternative sources of this peptide. It is often utilized as an endocrine hormone targeting the paracrine and autocrine systems.

The production of IGF-1 is stimulated by the presence of growth hormone
The production of IGF-1 is stimulated by the presence of growth hormone

The production of IGF-1 is stimulated by the presence of growth hormone and this is common for animals that lack adequate nutrition to supplement its own activities. When there is a lack of sensitivity or low production of the hormone as well as failure of the signaling pathway, then the animal’s body tends to fail in the production of an adequate amount of IGF. The production and administration of IGF are designed to combat issues of inadequate hormonal production or lack of receptor sensitivity. Over 98% of the insulin-like growth factor 1 produced binds with one of the six proteins and the most common binding is the IGFBP-3. This accounts for about 80% of all insulin-like growth factor 1 binding in the system.

Research done on mice showed that the insulin-like growth factor 1 is found in messenger RNA in the liver and it can be associated with casein which is negatively associated with a diet that lacks adequate protein. Recent studies revealed that the expression of the expression in plants can be used to generate a newer version and a more biologically active insulin-like growth factor 1 called rhIGF-1, especially in transgenic rice.

IGF DES Binding

The primary function of IGF DES  is to bind to specific receptors in the system especially IGF1R. This is present in all cell types and it helps make up different types of tissues. The binding of the peptide to receptors causes a signaling cascade which creates tyrosine kinase. Tyrosine kinase is an essential component because it helps the system initiate a signaling cascade that brings about changes and conversion of various molecules into a newer mechanism. The natural version of insulin-like growth factor 1 is the most potent in the signaling pathway of AKT. The initiation of the process helps to signal proliferation and cell growth. In some cases, the signal causes cellular death and generation of new cells. This keeps the cell cycle alive and it accentuates recovery process. IGF 1 is one of the primary mediators and the effects of the growth hormone cannot be underestimated. Growth hormone is produced in the somatotrophs in the pituitary gland. The hormone is usually produced alongside somatostatin and the amount per cell determines the overall amount of hormone produced.


Once growth hormone is produced in the pituitary gland, it is ferried through the bloodstream to stimulate the liver to produce the right amount of insulin-like growth factor 1. This in turn stimulates cells in the body to grow. In a situation where the pathways are not functioning, an external stimulation is required to bring the production of the hormone to a new level. Research showed that administration of IGF DES accentuates production of the growth hormone in the system and hyper-potent external stimuli are crucial in the overall functionality of cells. IGF DES and other tyrosine kinase receptors are used in different signaling pathways to accentuate the production of new cells. One main pathway that is regulated using P13K is essential in moving through downstream channels throughout the body. The deficiency of chemicals in the system is thought to bring about a recombinant vector which is classified as Laron syndrome. This is a common feature in beef cattle.

Synthesis of IGF DES  can be done using a wide array of chemical processes. This is essential because it helps to accentuate various processes in a biological system. The peptide is created through the truncation of the original insulin-like growth factor 1 molecule and replacing it with a different amino acid or eliminating them all together. The changes in the peptide sequence are essential because it increases its integrity and it’s half-life is extended, therefore able to reach different tissues in the body. Given the nature of the peptide, you the researcher can conduct several studies aimed at identifying the functionality of the peptide at a certain degree.

IGF DES and Hyperplasia

According to a recent study conducted on mice, the studies have shown that IGF DES accentuates a process called hypergenesis. This is a process which controls and regulates cellular proliferation and  is triggered by various causes. The causes include:

  • Chronic inflammatory response – this causes an increase in the proliferation of cells to fight off inflammation in the body.
  • Hormonal dysfunction – this is an important process and the production of IGF DES  is triggered because the body calls for the proliferation of cells to ward off various forms of ailments which could affect the endocrine system.
  • Increased demand – whenever there is a need for cells in an area, proliferation of cells is accentuated. This process is crucial in bringing up newer cells and creation of a base layer of the epidermis. This is essential because it makes up for skin loss.
IGF-1 for bodybuilders

IGF DES has the ability to accentuate production of more cells in the system. Research based on the animal subject indicated that the peptide promotes tissue development and growth. The study conducted on mice showed that it affects the skeletal and muscular growth in animal test subjects and it also may have an impact on neurological growth. Studies indicated that IGF DES  has an aptitude in increasing neuronal functionality and the structure of the neurons in its lifespan. Other studies have shown that it preserves nerve cell function and promotes the growth of new nerves. It is important to note that nerve cells are crucial for cell-to-cell communication and failure to adapt to the system any change of activity could cause cellular damage.

IGF DES Postulated Benefits

Studies conducted on animal test subjects have shown that the peptide has several potential benefits. Some of the benefits include:

  • Accelerate injury recovery – studies done on mice showed that the peptide has the ability to accentuate cellular proliferation and generation of newer cells. This is important especially when cells are damaged. The peptide will accentuate production of newer cells to repair and heal the injured site. The accelerated cellular proliferation will reduce the time taken for an injury to heal.
  • Accelerated muscle repair – IGF DES has mechanics which promotes hyperplasia. Hyperplasia is an increase in cellular division. An increase in cellular proliferation and enhanced myocytes differentiation is important in the generation of new muscle cells. The increase in muscular development will reduce the time taken for muscles to heal.
  • Slowed aging process – recent research studies have shown that IGF DES promotes cellular growth and this helps to reduce the breakdown of muscle fibers and control of elasticity in the muscles. This enables middle-aged and old rats to show a slower rate of tissue or cellular damage. This reduced cell damage and aging process.
recent research studies shown IGF DES promotes cellular growth
recent research studies shown IGF DES promotes cellular growth

IGF DES Side Effects

The scientific research studies have shown that IGF DES has potential benefits and the peptide has few negative side effects associated with its administration. The side effects include:

  • Swelling – this is a condition that tends to happen on the extremities of the animal test subject
  • Heart irregularities – conditions of this type of side effect include heart arrhythmia and cardiac arrest. In some cases, hypoglycemia may develop and this leads to depletion of glucose in blood. This is more or less associated with higher dosages. It is imperative to understand that the administration of the peptide should follow strict protocol and recommended dosage.

It is imperative to know that IGF DES  is solely for scientific research purposes and human consumption is not allowed. However, scientists are still researching on the potency and efficacy of the peptide to accentuate certain features.

Additional Information

Weight 0.005 g