Tesamorelin

Tesamorelin

$64.89

A hormone similar to the one normally released from the hypothalamus gland in the brain, used to reduce excess fat (lipodystrophy) in the abdomen or stomach in patients infected with human immunodeficiency virus (HIV)

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Product Description

Buy Tesamorelin Online- Peptide Research and analysis

Tesamorelin, mostly referred to as TH9507 in the past, is a peptide that is classified as undergrowth hormone releasing secretagogues. Growth hormone releasing factor or GHRF is a hormone responsible for the activation of the anterior pituitary lobe to secrete GH. The release of growth hormone increases metabolism, increases use of energy and enhances cell proliferation and maturity. Tesamorelin is a biosynthetic version of the natural GHRH. An indirect approach of the synthetic biopeptide is essential in maintaining stable levels of GH just like CJC-1295 DAC. Tesamorelin mimics the activity of growth hormone releasing hormone and induces lipolysis. This results in burning of fat in the peripheral organs. Moreover, it is effective in reducing dystrophy. The biopeptide is made up of molecular formula C221H366N72O67S and has the molecular mass of 5.135 kilo Daltons. The activity of tesamorelin is a stable analog of growth hormone releasing factor or GRF and induces GH in a specific manner.

Tesamorelin study
Tesamorelin study

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The tesamorelin peptide increases the level of growth hormone by improving pulsating release of the hormone in the anterior lobe of the pituitary gland. Moreover, studies revealed that the hormone increases the activity of brain cells. Tesamorelin increases the activity of biomarkers which are vital in indicating cognitive levels. Lipodystrophy is a condition which causes a significant change in the location of fat. This results in mass wasting and accumulation of fats in unnecessary locations. Sermorelin is similar to Tesamorelin and they work synergistically with GHRP-6, a hexapeptide secretagogue that accentuates the production of GH. The hormone is inhibited by somatostatin.

tesamorelin peptide is released from anterior lobe of pituitary gland
tesamorelin peptide is released from anterior lobe of pituitary gland

Research showed that the tesamorelin peptide is released from the anterior lobe of the pituitary gland in a pulsating manner. An increased level of Tesamorelin deactivates the functions of somatostatin. Tesamorelin increases plasma glucose significantly but it does not promote the deposit of fats on the peripheral or visceral organs. The sensitivity of the cells to the hormone is increased by other synergists such as hexarelin and growth hormone releasing peptide 2.

According to recent research, Tesamorelin does not change the level of transaminases such as alanine aminotransferase or aspartate aminotransferase. The lipid content reduces significantly with an increased level of Tesamorelin. This is mainly because the hormone increases metabolism and this prompts the burning of peripheral fat. C-reactive protein does not change with an increase in the level of the peptide. However, Tesamorelin increases the level of adiponectin as per recent study. Tesamorelin induces the release of growth hormone which is essential in cell division, development and maturity.

The levels of IGF-1 are increased with an increase in Tesamorelin levels. Elavated IGF-1 levels in turn increases the level of glycosylated hemoglobin. Studies revealed that the hypothalamic pituitary axis can be disrupted when the peptide level is high. This can result in glucose intolerance and hypersensitivity to mannitol. Synthetic Tesamorelin has a higher efficacy and potency than the regular growth hormone releasing hormone.

This promotes production and secretion of growth hormone-releasing hormone. Subsequent studies are being conducted on the activity of the hormone on controlled laboratory experiments.

growth hormone-releasing hormone levels
growth hormone-releasing hormone levels

Tesamorelin at a glance

The tesamorelin peptide contains forty-four amino acids in its chain and a trans-3-hexenoic acid group. According to research, the peptide is considered to be one of the growth releasing factors and it acts on the pituitary gland to accentuate the release of growth hormone. Some essential functions that are carried out by the pituitary gland include:

  • Metabolism
  • Growth
  • Pain relief
  • Temperature regulation

Specifically, tesamorelin  has been known to increase somatotrophic production of the growth hormone and it is considered as anabolic in nature. It is imperative to understand that the peptide plays some role in accentuating muscle and tissue repair. The peptide also determines lipolytic activity of the system, initiating a wide array of process which includes fatty acid breakdown and digestion of lipids that are stored in the system.

pep3

The storage of lipids usually occurs through triglycerides deposition on the peripheral organs. Free fatty acids are important in accentuating a wide array of processes in the system and its breakdown is essential because it reduces the ability to induce poor cellular development.

Conceptual Benefits of Tesamorelin

Recent research revealed that the tesamorelin peptide is beneficial in numerous ways. Research showed that when it is administered, it plays an important role in inducing lipolysis. This feature is important especially in patients with HIV as it helps reduce cases of lipodystrophy. This is a condition characterized by the loss of subcutaneous fat. In some cases, it leads to the accumulation of fats in an uneven manner in the body.

Conceptual Benefits of Tesamorelin
Conceptual Benefits of Tesamorelin

There is a postulate that the administration of the tesamorelin peptide would help alleviate the problem and accentuate the even deposition of fats across the system. This is an essential process which would in turn neutralize the effects of fat loss. In some cases, the accumulation of fats in peripheral and visceral organs would be alleviated. The scientific research study showed that the tesamorelin peptide has anabolic properties which makes the process of muscle and skeletal tissue production easier and vital.

Functionality of Tesamorelin

Recent research study revealed that the tesamorelin peptide has the ability to induce the pituitary gland to produce hormones in the system. Hormones are important because they induce important biological processes in the system. Activity of the pituitary gland located at the base of the brain below the hypothalamus is essential because without activity, important aspects such as growth, pain relief, metabolism and other essential factors would cease and this would affect the overall functionality of the organism.

It has been determined through research on animal subjects that the presence of the tesamorelin peptide can increase productions of the pituitary related to growth. Moreover, the peptide has the ability to increase production of insulin-like growth factor 1. Insulin-like growth factor 1 is essential because it stimulates the multiplication of cells and accentuates growth and development in the system.

Functionality of Tesamorelin
Functionality of Tesamorelin

This has led to the determination that the tesamorelin peptide is anabolic in nature and can play an important role in influencing the repair of skeletal and muscular tissues. The peptide is also known to be lipolytic in nature, and this is the ability to breakdown lipids that are stored. The process usually involves hydrolysis of triglycerides into free fatty acids and glycerol.

 

Tesamorelin and HIV-Associated Lipodystrophy

Recent research studies on animal test subjects have revealed that Tesamorelin has the ability to induce lipolysis. This is important because further research and identification of the positive effects of the peptide will help in treating the human immuno deficiency related lipodystrophy. This is a condition characterized by accumulation of fat in unusual places like the back and the loss of subcutaneous fat on the legs, arms and face.

Tesamorelin and HIV-Associated Lipodystrophy
Tesamorelin and HIV-Associated Lipodystrophy

The studies indicated that the presence of the tesamorelin peptide could induce a better distribution of fats and this is essential because lipolysis will be even. The net effect of the peptide is neutralization of the features of fat loss and the animal test subject will have an even distribution of fats in the system. Moreover, unorthodox deposition of fats would reduce immensely. Research studies have revealed that tesamorelin can be manipulated to give better results in the future. However, it is essential to note that Tesamorelin is still under research and is for scientific research purposes only. Human consumption is not allowed.

Tesamorelin and Tissue Regulation

A postulated indicated that Tesamorelin is essential in accentuating tissue regulation. This is an essential feature because of the inherent nature of the tesamorelin peptide. It could help in making regulatory process easier especially when it comes to muscle and skeletal efficiency. When conducting research with the peptide,it is imperative to understand the benefits that come with it.

When administered to mice, tesamorelin was seen to decrease the amount of extra fat in the abdominal area and this is important especially in tissue regulation. Tissue regulation is an essential feature which could help in alleviating various conditions. Although the tesamorelin peptide did not cause a significant weight loss, its injection is often classified as a growth hormone releasing factor and it works by increasing production of the natural substance which could increase the amount of body fat.

Tesamorelin and Tissue Regulation
Tesamorelin and Tissue Regulation

The subcutaneous deposition of various fat components brings about change in a biological system and monitoring of the situation is essential because it could affect the overall effort of the study.

According to previous studies, the tesamorelin peptide is injected once a day. Directions for use should be followed effectively. This is essential because it will help reduce adverse effects of various conditions which occur in a biological system. Before the peptide is injected, it is imperative that you read the manufacturer’s’ information and possible side effects to determine if any change would cause adverse side effects on the organism.

Tesamorelin is supplied in freeze-dried vials and the vials contain a liquid which is used to mix it. The liquid is saline or bacteriostatic water which does not contain any bacteria or microorganism. Some side effects of injecting the tesamorelin peptide include redness of the area, irritation, scarring and bruising of the affected area.

Tesamorelin is supplied in freeze-dried vials
Tesamorelin is supplied in freeze-dried vials

This is a common feature according to a recent study. It is important to note that the peptide should not be injected in an area with hard bumps or where a previous injection was done. Choose a different area to avoid bruising and damage of the epidermal layer.

Dosage

The peptide is supplied as a lyophilized or freeze dried vial. It is imperative to note that the administration of the tesamorelin peptide should occur after reconstituting the peptide using bacteriostatic or saline water. Once you have reconstituted the vial, it is essential that you do not store any. It is recommended that you reconstitute the amount that you need to use immediately. Storing any amount of the peptide would result in its deterioration and this would affect the overall result.

Dosage
Dosage

You should always look for a solution of the peptide before injecting on the test subject. Do not use the tesamorelin peptide is the injection has obtained undesirable characteristics such as cloudiness, color or has particles. The peptide should be administered in the clearest manner and the identification process should be unique. It is vital to note that regular administration of tesamorelin could bring the desired effect because of the efficacy and potency of the peptide.

Moreover, the syringe used in the administration should be used only once. This is important because it would prevent cross contamination of test samples and the research findings will be legitimate. Consistency and reproducibility of results is a key feature and in most cases. A study cannot be used as a benchmark if the tesamorelin peptide is laced with unwanted components or if there is contamination of any kind.

recent study
recent study

In addition, a recent study revealed that the peptide can interact with other drugs if they are co-administered together. Ingredients of Tesamorelin reacts with any kind of mannitol or medications containing this component. In addition, mice that have undergone previous study surgery should not be used for the experiment because hormonal production will interfere and the legitimacy of results.

Some side effects that occurred in animal test subjects include swelling of the lower limbs, numbness, tingling, nausea, blurry vision, itching and redness of the administration area. It is imperative that you store the tesamorelin peptide at 2-8 degree Celsius to avoid disintegration of the amino acids in the chain.

Keep the vials tightly closed and away from direct sunlight. You should try with small dosages before you can move to larger doses. You may begin with 0.5 milligrams before moving on to 2.0 milligrams in an additional 0.5 milligrams for any increase. This will help you ascertain the level of activity of the peptide. Moreover, you will understand where tolerance becomes a problem.

Additional Information

Weight 0.005 g